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Collagen Peptides, in Association with Vitamin C, Sodium Hyaluronate, Manganese and Copper, as Part of the Rehabilitation Project in the Treatment of Chronic Low Back Pain
Plain-language guide to PMID 33568038 (2022): randomized controlled trial study of Copper (Supplement), chronic pain: fibromyalgia & crps.
Key Facts
- PMID
- 33568038
- Journal
- Endocrine, metabolic & immune disorders drug targets
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Farì G et al. (11 authors)
- DOI
- 10.2174/1871530321666210210153619
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial paper looks at Copper (Supplement) in the context of chronic pain: fibromyalgia & crps.
Low back pain (LBP) is a frequent symptom.
Among the causes that can determine it, lumbar osteoarthritis plays an important role.
Oral supplementation with collagen peptides represents a new therapeutic possibility in osteoarthritis.
Who Took Part
The age groups tagged for this paper are adults and middle-aged adults, both men and women.
Sixty patients were recruited and randomly divided into two groups (Group A and B).
Group A performed only kinesitherapy, Group B carried out the same kinesitherapy combined with the daily administration of food supplements such as Fortigel®, Vitamin C, sodium hyaluronate, manganese and copper, during the whole treatment period.
How the Study Was Run
The researchers set it up as a randomized study.
Because people in this Copper (Supplement) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Patients were evaluated at the time of recruitment (T0), at the end of the treatment (T1 - 3 weeks after T0) and 6 weeks after T1 (T2).
The outcome measures used were: Visual Analogue Scale (VAS), Oswestry Disability Index (ODI), and Short Form-12 (SF-12).
What Was Measured
Topics PubMed links to this paper include Ascorbic Acid, Chronic Pain, Collagen, Combined Modality Therapy, Copper, Exercise Therapy and Hyaluronic Acid.
The authors tagged it with the keywords Low back pain, McKenzie method, collagen peptides, hyaluronate sodium, oral supplementation and osteoarthritis.
What This Means in Plain Language
The paper is a randomized study of Copper (Supplement) in people with chronic pain: fibromyalgia & crps.
Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2022 (Endocrine, metabolic & immune disorders drug targets), a journal based in United Arab Emirates.
More context: the Copper (Supplement) compound page, Chronic pain: fibromyalgia & CRPS research.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.