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Oral nutritional supplement use is weakly associated with increased subjective health-related quality of life in malnourished older adults: a multicentre randomised controlled trial.
Plain-language guide to PMID 33678201 (2022): multicenter randomized controlled trial of Copper (Supplement) in 409 patients.
Key Facts
- PMID
- 33678201
- Journal
- The British journal of nutrition
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Söderström L et al. (3 authors)
- DOI
- 10.1017/S0007114521000805
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Copper (Supplement).
The intervention started at discharge from hospital, with HRQoL measured using European QoL five-dimension, three-level (EQ-5D-3L) and European QoL-visual analogue scale (EQ-VAS) at baseline and at 6-month, 1-year and 3-year follow-ups.
Data were analysed using the Kruskal-Wallis test and multiple linear regression.
Who Took Part
The abstract describes 409 patients taking part.
By PubMed's age tags, the people studied were older adults.
Patients were randomised into four arms: DA, ONS, DA + ONS or routine care (control).
How the Study Was Run
The researchers set it up as a randomized and multicenter study.
Random assignment meant chance, not the researchers, decided who got Copper (Supplement) and who got the comparison, which limits bias.
Running at several centres spread the Copper (Supplement) study over different clinics and patient groups.
What Was Measured
The intervention started at discharge from hospital, with HRQoL measured using European QoL five-dimension, three-level (EQ-5D-3L) and European QoL-visual analogue scale (EQ-VAS) at baseline and at 6-month, 1-year and 3-year follow-ups.
Data were analysed using the Kruskal-Wallis test and multiple linear regression.
PubMed files the paper under topics including Dietary Supplements, Malnutrition, Nutrition Therapy, Nutritional Status and Quality of Life.
Author keywords: Dietary advice, Older adults, Oral nutritional supplementation and Randomised controlled trial.
What This Means in Plain Language
The paper is a randomized and multicenter study of Copper (Supplement) in 409 patients.
With several hundred people or more, it is a fairly large study for this kind of research.
The publication is from 2022 (The British journal of nutrition), a journal based in England.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.