← Human Trials & Peer-Reviewed Studies

The Effect of a Multi-ingredient Supplement on Resistance Training-induced Adaptations.

Plain-language guide to PMID 33756525 (2021): double-blind randomized controlled trial of Copper (Supplement).

Key Facts

PMID
33756525
Journal
Medicine and science in sports and exercise
Year
2021
Study type
Randomized Controlled Trial
Authors
Wageh M et al. (6 authors)
DOI
10.1249/MSS.0000000000002641
Registered trial
NCT03525197

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Copper (Supplement).

The researchers aimed to determine the effect of a high-quality multi-ingredient nutritional supplement (SUPP) versus an isonitrogenous (lower protein quality), isoenergetic placebo (PL) on RET-induced gains in lean body mass (LBM), muscle thickness, and muscle cross-sectional area (CSA).

The researchers hypothesized that RET-induced gains in LBM and muscle CSA would be greater in SUPP versus PL.

Why It Was Studied

Resistance exercise training (RET) induces muscle hypertrophy that, when combined with co-temporal protein ingestion, is enhanced.

However, fewer studies have been conducted when RET is combined with multi-ingredient supplements.

Who Took Part

By PubMed's age tags, the people studied were young adults, both men and women.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

Random assignment meant chance, not the researchers, decided who got Copper (Supplement) and who got the comparison, which limits bias.

As a double-blind Copper (Supplement) study, the assignments were hidden from both participants and investigators until the end.

The comparison arm used a placebo, so changes seen with Copper (Supplement) could be set against what happens without it.

What Was Measured

The subject headings attached to it are Adaptation, Physiological, Body Composition, Dietary Supplements, Muscle Strength, Muscle, Skeletal and Resistance Training.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement).

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2021 (Medicine and science in sports and exercise), a journal based in United States.

More context: the Copper (Supplement) compound page, all human trials.

Our Notes on the Compound

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.