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The effect of vitamin D and magnesium supplementation on the mental health status of attention-deficit hyperactive children: a randomized controlled trial.

Plain-language guide to PMID 33865361 (2021): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 66 children.

Key Facts

PMID
33865361
Journal
BMC pediatrics
Year
2021
Study type
Randomized Controlled Trial
Authors
Hemamy M et al. (7 authors)
DOI
10.1186/s12887-021-02631-1

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

The aim of this study is to determine the effect of vitamin D and magnesium supplementation on mental health in children with ADHD.

Strengths and difficulties questionnaire was used to evaluate children's mental health at baseline and the end of the study.

Why It Was Studied

Attention-Deficit / Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder, characterized by varying severity in attention deficit and hyperactivity.

Who Took Part

The abstract describes 66 children taking part.

The age groups tagged for this paper are children.

The researchers conducted a randomized, double blind, placebo-controlled clinical trial of 66 children with ADHD.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

What Was Measured

PubMed files the paper under topics including Attention Deficit Disorder with Hyperactivity, Dietary Supplements, Health Status, Magnesium and Vitamin D.

The authors tagged it with the keywords Attention-deficit hyperactivity disorder, Randomized controlled trial and Supplementation.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 66 children.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2021 (BMC pediatrics), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.