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Analysis of Effectiveness of a Supplement Combining Harpagophytum procumbens, Zingiber officinale and Bixa orellana in Healthy Recreational Runners with Self-Reported Knee Pain: A Pilot, Randomized, Triple-Blind, Placebo-Controlled Trial.
Plain-language guide to PMID 34067240 (2021): randomized controlled trial of Copper (Supplement).
Key Facts
- PMID
- 34067240
- Journal
- International journal of environmental research and public health
- Year
- 2021
- Study type
- Randomized Controlled Trial
- Authors
- González-Gross M et al. (11 authors)
- DOI
- 10.3390/ijerph18115538
- Registered trial
- NCT04150211
What This Study Did, in Plain Language
What Was Tested
Researchers studied Copper (Supplement) in this randomized controlled trial publication.
The aim was to analyze the effect of a four-week supplementation with a mixture of Harpagophytum procumbens, Zingiber officinale and Bixa orellana on males, middle-aged, RR with an undiagnosed knee discomfort.
Why It Was Studied
A randomized triple-blind placebo-control trial was conducted among male RR aged 40-60 years suffering from self-declared knee discomfort after training.
At pre- and post-intervention, assessment of routine blood biomarkers, body composition, running biomechanics and body temperature was performed using standardized procedures.
Who Took Part
PubMed indexes the participants as middle-aged adults, men only.
How the Study Was Run
In design terms this was a randomized and placebo-controlled study.
Random assignment meant chance, not the researchers, decided who got Copper (Supplement) and who got the comparison, which limits bias.
A placebo (an inactive look-alike) gave the Copper (Supplement) group a baseline to be compared against.
What Was Measured
At pre- and post-intervention, assessment of routine blood biomarkers, body composition, running biomechanics and body temperature was performed using standardized procedures.
PubMed files the paper under topics including Bixaceae, Dietary Supplements, Zingiber officinale, Harpagophytum, Pain and Self Report.
Author keywords: Bixa orellana, Harpagophytum procumbens, biomechanical phenomena, knee joint inflammation, recreational runners and thermography.
What This Means in Plain Language
The paper is a randomized and placebo-controlled study of Copper (Supplement).
The publication is from 2021 (International journal of environmental research and public health), a journal based in Switzerland.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.