Measurement of serial serum total and acylated ghrelin levels in critically ill patients: A prospective and observational pilot study

What Was Tested

This observational study looks at Ghrelin.

The aim of this study was to determine serum total and acylated ghrelin levels serially in critically ill patients.

Why It Was Studied

Ghrelin is a hormone that regulates appetite and energy metabolism.

The change of serial serum total and acylated ghrelin levels during hospital stays of critical patients are unknown.

Who Took Part

PubMed indexes the participants as teenagers, adults, middle-aged adults and older adults.

Patients who were >18 years old and stayed in ICU for >48 h were included in the study.

Serum total and acylated ghrelin concentrations were measured at baseline in all participants and serially on the 2nd, 5th, and 10th day after entry into the study in those who remained in the ICU.

How the Study Was Run

The design is described as pilot.

It is described as a pilot, a small early test of whether a larger Ghrelin study would be practical.

This prospective study was performed in the ICU.

What Was Measured

The change of serial serum total and acylated ghrelin levels during hospital stays of critical patients are unknown.

Topics PubMed links to this paper include Appetite, Critical Illness, Ghrelin and Pilot Projects.

Author keywords: intensive care unit and mortality.

What This Means in Plain Language

The paper is a pilot study of Ghrelin.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2022 (Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition), a journal based in United States.

More context: the Ghrelin compound page, all human trials.