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Biological and clinical effects of a resveratrol-based multivitamin supplement on intracytoplasmic sperm injection cycles: a single-center, randomized controlled trial.

Plain-language guide to PMID 34338114 (2022): randomized controlled trial of Copper (Supplement) in 101 women.

Key Facts

PMID
34338114
Journal
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Year
2022
Study type
Randomized Controlled Trial
Authors
Gerli S et al. (9 authors)
DOI
10.1080/14767058.2021.1958313
Registered trial
NCT04386499

What This Study Did, in Plain Language

What Was Tested

Researchers studied Copper (Supplement) in this randomized controlled trial publication.

The aim of this study was to evaluate the biological and clinical impact of a resveratrol-based multivitamin supplement on intracytoplasmatic sperm injection (ICSI) cycles.

Why It Was Studied

Resveratrol display's positive effects on follicle growth and development in preclinical studies while there is scantly information from clinical trials.

Who Took Part

The study group was 101 women.

PubMed tags the participants as both men and women.

A randomized, single-center controlled trial conducted at the University Center of Assisted Reproductive Technologies involving 101 women infertile women undergoing ICSI cycles was conducted.

How the Study Was Run

The design is described as randomized.

Because people in this Copper (Supplement) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The primary outcomes were the number of developed mature follicles (>16 mm), total oocytes and MII oocytes recovered, the fertilization rate and the number of cleavage embryos/blastocysts obtained.

What Was Measured

PubMed files the paper under topics including Sperm Injections, Intracytoplasmic, Resveratrol, Infertility, Female, Embryo Transfer, Abortion, Spontaneous, Semen and Pregnancy Rate.

Author keywords: assisted reproductive technologies, intracytoplasmic sperm injection and oocyte.

What This Means in Plain Language

The paper is a randomized study of Copper (Supplement) in 101 women.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2022 (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians), a journal based in England.

More context: the Copper (Supplement) compound page, all human trials.

Our Notes on the Compound

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.