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The effect of acute exercise on pre-prandial ghrelin levels in healthy adults: A systematic review and meta-analysis.

Plain-language guide to PMID 34391825 (2021): meta-analysis of Ghrelin.

Key Facts

PMID
34391825
Journal
Peptides
Year
2021
Study type
Meta-Analysis
Authors
Anderson KC et al. (6 authors)
DOI
10.1016/j.peptides.2021.170625

What This Paper Covers, in Plain Language

What It Covers

The paper reports a study of Ghrelin, published as a meta-analysis.

Ghrelin is a gut hormone with numerous physiological effects, including the regulation of energy balance, insulin sensitivity, vascular health, and body composition.

Exercise is a therapeutic option that can potentially optimize ghrelin levels.

Who the Included Studies Covered

PubMed tags the participants as both men and women.

The following criteria was determined a priori for article inclusion: (i) the study was a randomized controlled trial (RCT),(ii) exercise was an acute bout, (iii) the exercise bout for the intervention group(s)/condition was structured, (iv) the control group/condition received no exercise, (v) participants were adults age 18 or older, (vi) ghrelin was sampled through blood, (vii) there was at least one baseline measure and one post-exercise measure of ghrelin, (viii) there were at least 3 timepoints where ghrelin was measured while participants were fasted to allow for pre-prandial total area-under-the-curve (AUCtotal) calculation, (ix) participants were healthy with no overt disease, (x) interventions were carried out without any environmental manipulations.

How the Review Was Done

Electronic databases (PubMed, Medline, SPORTDiscus, Web of Science, and Google Scholar) were searched with articles published through August 2020.

What Was Measured

Exercise is a therapeutic option that can potentially optimize ghrelin levels.

PubMed files the paper under topics including Acylation, Body Mass Index, Energy Metabolism, Exercise, Fasting and Ghrelin.

Author keywords: Acute exercise, Gut hormones and Physical activity.

What This Means in Plain Language

This is a meta-analysis of Ghrelin.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2021 (Peptides), a journal based in United States.

More context: the Ghrelin compound page, all human trials.

Our Notes on the Compound

Ghrelin: A 28-amino-acid stomach hormone that signals hunger and triggers growth hormone release; studied in human trials as an infusion.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.