Vitamin D and Muscle Health: A Systematic Review and Meta-analysis of Randomized Placebo-Controlled Trials.

What It Covers

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a meta-analysis.

The objective of this study was to investigate the effects of vitamin D supplementation versus placebo on muscle health.

Why It Was Studied

For this systematic review and trial-level meta-analysis of placebo-controlled trials, a systematic search of randomized controlled trials published until October 2020 was performed in Medline, Embase, and Google Scholar.

The predefined endpoints were physical performance reported as timed up and go test (TUG; seconds), chair rising test (seconds), 6-minute walking distance (m), and Short Physical Performance Battery (SPPB; points).

How the Review Was Done

In total, 54 randomized controlled trials involving 8747 individuals were included.

What Was Measured

For this systematic review and trial-level meta-analysis of placebo-controlled trials, a systematic search of randomized controlled trials published until October 2020 was performed in Medline, Embase, and Google Scholar.

The predefined endpoints were physical performance reported as timed up and go test (TUG; seconds), chair rising test (seconds), 6-minute walking distance (m), and Short Physical Performance Battery (SPPB; points).

Topics PubMed links to this paper include Cholecalciferol, Dietary Supplements, Hand Strength, Muscles, Postural Balance, Randomized Controlled Trials as Topic and Time and Motion Studies.

The authors tagged it with the keywords CLINICAL TRIAL, DXA, NUTRITION, SKELETAL MUSCLE and VITAMIN D.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.

The publication is from 2021 (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.