Vitamin D and Hashimoto's Thyroiditis: Observations from CROHT Biobank.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as an observational study.

The aims of this study were to evaluate: (1) associations of vitamin D with the presence/severity of Hashimoto's thyroiditis (HT) and (2) correlations of vitamin D with thyroid-related phenotypes.

Why It Was Studied

(1) Vitamin D levels, and proportions of vitamin D deficiency, were compared between HT cases and controls.

HT patients were additionally divided into two groups (MILD and OVERT) to take into account HT severity.

Who Took Part

According to the abstract, 461 patients were involved.

The age groups tagged for this paper are adults and middle-aged adults, both men and women.

Total 25(OH)D (vitamin D in the text) was measured from stored serum samples of 461 HT patients and 176 controls from a Croatian Biobank of HT patients (CROHT).

What Was Measured

(1) Vitamin D levels, and proportions of vitamin D deficiency, were compared between HT cases and controls.

(2) Correlations between vitamin D and 10 clinical phenotypes in all HT patients and two subgroups of HT patients were tested using the Spearman correlation test.

The subject headings attached to it are Biological Specimen Banks, Blood Pressure, Case-Control Studies, Croatia, Hashimoto Disease, Phenotype and Seasons.

The authors tagged it with the keywords Hashimoto’s thyroiditis, thyroid autoimmunity, thyroid stimulating hormone (TSH), thyrotropin and vitamin D.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 461 patients.

With several hundred people or more, it is a fairly large study for this kind of research.

The publication is from 2021 (Nutrients), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.