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Effect of Vitamin D Supplementation in Type 2 Diabetes Patients with Tuberculosis: A Systematic Review.
Plain-language guide to PMID 34473618 (2022): systematic review of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
Key Facts
- PMID
- 34473618
- Journal
- Current diabetes reviews
- Year
- 2022
- Study type
- Systematic Review
- Authors
- Patel DG et al. (10 authors)
- DOI
- 10.2174/1573399817666210902144539
What This Paper Covers, in Plain Language
What It Covers
The paper reports a study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement), published as a systematic review.
Vitamin D affects the immune response, suppresses Mycobacterium tuberculosis (Mtb) growth, and affects insulin secretion.
The present systematic review determines the effect of vitamin D supplementation on clinical and therapeutic outcomes of DM-TB patients.
A comprehensive literature search was carried out in PubMed, Cochrane, Web of Science, and Scopus database to determine eligible studies from inception to January 2021.
Why It Was Studied
Diabetes mellitus (DM) and tuberculosis (TB) have been recognized as reemerging epidemics, especially in developing countries.
Vitamin D has been found as a link between DM-TB co-morbidity.
How the Review Was Done
Out of the 639 articles retrieved, three randomized controlled trials (RCTs) were included in the systematic review.
What Was Measured
The subject headings attached to it are Blood Glucose, Cholecalciferol, Diabetes Mellitus, Type 2, Dietary Supplements, Tuberculosis, Tuberculosis, Pulmonary and Vitamin D.
Author keywords: TB score, sputum smear conversion, systematic review and vitamin D3 supplement.
What This Means in Plain Language
This is a systematic review of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2022 (Current diabetes reviews), a journal based in United Arab Emirates.
More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.
Our Notes on the Compounds
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.