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The correlation between serum selenium, zinc, and COVID-19 severity: an observational study.
Plain-language guide to PMID 34479494 (2021): observational study of Vitamin D, K2, Magnesium and Zinc in 19 patients.
Key Facts
- PMID
- 34479494
- Journal
- BMC infectious diseases
- Year
- 2021
- Study type
- Observational Study
- Authors
- Razeghi Jahromi S et al. (14 authors)
- DOI
- 10.1186/s12879-021-06617-3
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this observational study publication.
Without an adequate immune response, SARS-CoV2 virus can simply spread throughout the body of the host.
Two of the well-known immunonutrients are selenium (Se) and zinc (Zn).
Who Took Part
According to the abstract, 19 patients were involved.
Eighty-four COVID-19 patients were enrolled in this observational study.
Patients were diagnosed based on an infectious disease specialist diagnosis, using WHO interim guidance and the recommendations of the Iranian National Committee of Covid-19.
How the Study Was Run
The patients with acute respiratory tract infection symptoms were checked for compatibility of chest computed tomography (CT) scan results with that of Covid-19 and Real-time polymerase chain reaction (RT-PCR) for corona virus infection.
The severity of Covid-19 was categorized into three groups (mild, moderate, and severe) using CDC criteria.
Serum Zn and Se level of all subjects was measured.
The severity of the disease was determined only once at the onset of disease.
What Was Measured
Thus, in the current study the researchers aimed at evaluating the correlation between serum Se and Zn status and COVID-19 severity.
The subject headings attached to it are COVID-19, Iran, RNA, Viral, SARS-CoV-2, Selenium and Zinc.
Author keywords: Immunity and Nutritional status.
What This Means in Plain Language
This is an observational study of Vitamin D, K2, Magnesium and Zinc in 19 patients.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2021 (BMC infectious diseases), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.