Effects of Vitamin D Supplementation on Orthostatic Hypotension: Results From the STURDY Trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Who Took Part

PubMed indexes the participants as adults and older adults, both men and women.

Participants were also asked about OH symptoms during the assessment and the preceding month.

How the Study Was Run

The design is described as randomized and double-blind.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

OH was determined at baseline, 3, 12, and 24 months by taking the difference between seated and standing blood pressure (BP).

OH was defined as a drop in systolic or diastolic BP of at least 20 or 10 mm Hg after 1 minute of standing.

What Was Measured

The subject headings attached to it are Cholecalciferol, Dietary Supplements, Hypotension, Orthostatic, Vitamin D and Vitamins.

The authors tagged it with the keywords blood pressure, hypertension, orthostatic hypotension, trial and vitamin D3.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2022 (American journal of hypertension), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.