← Human Trials & Peer-Reviewed Studies
Handwashing Results in Incomplete Nicotine Removal from Fingers of Individuals who Smoke: A Randomized Controlled Experiment.
Plain-language guide to PMID 34634832 (2022): randomized controlled trial of Therapeutic nicotine (patch, non-peptide).
Key Facts
- PMID
- 34634832
- Journal
- American journal of perinatology
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Northrup TF et al. (10 authors)
- DOI
- 10.1055/s-0041-1736287
- Registered trial
- NCT04155697
What This Study Did, in Plain Language
What Was Tested
Researchers studied Therapeutic nicotine (patch, non-peptide) in this randomized controlled trial publication.
Tobacco residue, also known as third-hand smoke (THS), contains toxicants and lingers in dust and on surfaces and clothes.
THS also remains on hands of individuals who smoke, with potential transfer to infants during visitation while infants are hospitalized in neonatal intensive care units (NICUs), raising concerns (e.g., hindered respiratory development) for vulnerable infants.
Why It Was Studied
· NICU infants may be exposed to THS via visitors. · THS is not eliminated by HW or sanitizing. · THS removal protections for NICU infants are needed.
Who Took Part
By PubMed's age tags, the people studied were adults.
A cross-sectional sample was recruited to complete an interview, carbon monoxide breath samples, and three nicotine wipes of separate fingers (thumb, index, and middle).
Eligible participants (n = 14) reported current smoking (verified with breath samples) and were randomly assigned to 30 seconds of HW (n = 7) or alcohol-based sanitization (n = 7), with the order of finger wipes both counterbalanced and randomly assigned.
How the Study Was Run
The design is described as randomized.
The participants were allocated by chance, so the Therapeutic nicotine (patch, non-peptide) group and the comparison group should start out alike.
After randomization, the first finger was wiped for nicotine.
Participants then washed or sanitized their hands and finger two was wiped 5 minutes later.
An interview assessing tobacco/nicotine use and exposure was then administered, followed by a second breath sample and the final finger wipe (40-60 minutes after washing/sanitizing).
What Was Measured
Topics PubMed links to this paper include Nicotine, Tobacco Smoke Pollution, Hand Disinfection, Cross-Sectional Studies and Smoking.
What This Means in Plain Language
The paper is a randomized study of Therapeutic nicotine (patch, non-peptide).
The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2022 (American journal of perinatology), a journal based in United States.
More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.
Our Notes on the Compound
Therapeutic nicotine (patch, non-peptide): Pure nicotine as a signaling tool, separated from smoking and vaping.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.