Supplementation of Vitamin D in the Postdelivery Period of Women with Previous Gestational Diabetes Mellitus: Systematic Review and Meta-Analysis of Randomized Trials.

Plain-language guide to PMID 34670305 (2021): meta-analysis of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID: 34670305
Journal: Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia
Year: 2021
Study type: Meta-Analysis
Authors: Kron-Rodrigues MR et al. (3 authors)
DOI: 10.1055/s-0041-1734000

What This Paper Covers, in Plain Language

What It Covers

This meta-analysis looks at Vitamin D, K2, Magnesium and Zinc.

To evaluate the effects of vitamin D supplementation in the postpartum period of women with previous gestational diabetes mellitus (GDM).

Who the Included Studies Covered

PubMed tags the participants as women only.

Randomized clinical trials of pregnant women with GDM of any chronological, gestational age and parity, with no history of previous disease who received vitamin D supplementation in the prenatal and/or postpartum period and were evaluated in the postpartum period were included.

Serum vitamin D concentration (25-hydroxyvitamin D in nmol/L), fasting blood glucose, glycated hemoglobin, serum calcium concentration, homeostatic model assessment of insulin resistance (HOMA-IR), quantitative insulin sensitivity check index (QUICKI), parathyroid hormone (PTH) and body mass index (BMI) were evaluated.

How the Review Was Done

The PubMed, EMBASE, Cochrane, and LILACS databases were consulted until July 2019.

Similar results in at least two trials were plotted using the RevMan 5; Cochrane Collaboration, Oxford, Reino Unido.

The quality of the evidence was generated according to the classification, development, and evaluation of the classification of the recommendations.

What Was Measured

Topics PubMed links to this paper include Diabetes, Gestational, Dietary Supplements, Randomized Controlled Trials as Topic, Vitamin D and Vitamins.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2021 (Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia), a journal based in Brazil.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Vitamin D, K2, Magnesium and Zinc in the library

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.