Vitamin D Supplementation and Mental Health in Inflammatory Bowel Diseases and Irritable Bowel Syndrome Patients: A Systematic Review.

What It Covers

This systematic review looks at Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

The aim of the present study was to conduct a systematic review of the literature presenting the data regarding the influence of vitamin D supplementation on mental health in adults with inflammatory and functional bowel diseases, including IBDs and IBS.

Why It Was Studied

This study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and registered in the International Prospective Register of Systematic Reviews (PROSPERO) database (Registration number CRD42020155779).

The human studies eligible to be included in the review should have described any intervention involving vitamin D as a supplement in a group of adult patients suffering from IBDs and/or IBS and should have assessed any component of mental health, but studies presenting the effects of combined supplementation of multiple nutrients were excluded.

How the Review Was Done

A systematic search of the PubMed and Web of Science databases was performed, and the intervention studies published until September 2021 were included.

Finally, 10 studies (four for IBDs and six for IBS) were selected for the current systematic review, and their quality was assessed using the Newcastle-Ottawa Scale (NOS).

What Was Measured

The human studies eligible to be included in the review should have described any intervention involving vitamin D as a supplement in a group of adult patients suffering from IBDs and/or IBS and should have assessed any component of mental health, but studies presenting the effects of combined supplementation of multiple nutrients were excluded.

After eliminating the duplicates, a total of 8514 records were screened and assessed independently by two researchers.

Topics PubMed links to this paper include Dietary Supplements, Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Mental Health and Vitamin D.

Author keywords: anxiety, depression, disease-specific quality of life, inflammatory bowel diseases (IBD), irritable bowel syndrome (IBS) and quality of life.

What This Means in Plain Language

This is a systematic review of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

The publication is from 2021 (Nutrients), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.