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The effects of consuming a low-fat yogurt fortified with nano encapsulated vitamin D on serum pro-oxidant-antioxidant balance (PAB) in adults with metabolic syndrome; a randomized control trial.

Plain-language guide to PMID 34781136 (2021): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 139 adults.

Key Facts

PMID
34781136
Journal
Diabetes & metabolic syndrome
Year
2021
Study type
Randomized Controlled Trial
Authors
Taghizadeh N et al. (16 authors)
DOI
10.1016/j.dsx.2021.102332

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

The current study aimed to assess the effect of fortified yogurt with nano-encapsulated vitamin D on serum pro-oxidant anti-oxidant balance (PAB) in adults with or without metabolic syndrome.

Before and after the intervention period, blood sample was taken to determine the serum levels of vitamin D, pro-oxidant-antioxidant balance (PAB), and high-sensitivity C-reactive protein (hs-CRP).

Who Took Part

The abstract describes 139 adults taking part.

The age groups tagged for this paper are adults and middle-aged adults, both men and women.

The laboratory tests were checked at baseline and at the end of the treatment.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

What Was Measured

Topics PubMed links to this paper include Antioxidants, Diet, Fat-Restricted, Food, Fortified, Metabolic Syndrome, Nanocapsules, Oxidants and Reactive Oxygen Species.

The authors tagged it with the keywords Fortification, Nano encapsulation, Prooxidant-antioxidant balance and Vitamin D.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 139 adults.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2021 (Diabetes & metabolic syndrome), a journal based in Netherlands.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.