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Influence of Vitamin D Supplementation on Mental Health in Diabetic Patients: A Systematic Review.

Plain-language guide to PMID 34835934 (2021): systematic review of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
34835934
Journal
Nutrients
Year
2021
Study type
Systematic Review
Authors
Guzek D et al. (6 authors)
DOI
10.3390/nu13113678

What This Paper Covers, in Plain Language

What It Covers

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a systematic review.

The aim of the present study was to conduct a systematic review of the literature presenting the data regarding the influence of vitamin D supplementation on mental health in diabetic adults.

Why It Was Studied

This study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and registered in the International Prospective Register of Systematic Reviews (PROSPERO) database (Registration number CRD42020155779).

After removing duplicate records, a total of 8514 publications were screened and assessed independently by two researchers, based on their title, abstract, and full text.

Who the Included Studies Covered

The age groups tagged for this paper are middle-aged adults and older adults, both men and women.

The human studies were included if an adult sample of diabetic individuals received vitamin D supplementation during the intervention and its effect on any mental health aspect was assessed, but studies presenting the influence of combined supplementation of multiple nutrients were excluded.

How the Review Was Done

A systematic search of the PubMed and Web of Science databases was performed, and the intervention studies published until September 2021 were included in the review.

Finally, six studies were included in the current systematic review, and the risk of bias was evaluated using the Newcastle-Ottawa Scale (NOS).

What Was Measured

After removing duplicate records, a total of 8514 publications were screened and assessed independently by two researchers, based on their title, abstract, and full text.

The subject headings attached to it are Anxiety, Depression, Diabetes Mellitus, Dietary Supplements, Mental Health, Nutrition Therapy and Quality of Life.

Author keywords: cholecalciferol, health-related quality of life (HRQOL), stress, supplementation and vitamin D.

What This Means in Plain Language

This is a systematic review of Vitamin D, K2, Magnesium and Zinc.

The publication is from 2021 (Nutrients), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.