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Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial.
Plain-language guide to PMID 34838305 (2022): pilot randomized controlled trial of Copper (Supplement).
Key Facts
- PMID
- 34838305
- Journal
- Journal of pediatric surgery
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Chung KJ et al. (6 authors)
- DOI
- 10.1016/j.jpedsurg.2021.10.032
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Copper (Supplement).
Umbilical granuloma is a common infantile condition which usually responds to non operative management.
Copper sulphate (CuSO4) is often used as chemical cauterization but can cause superficial skin burns.
Who Took Part
The age groups tagged for this paper are children.
The researchers included children who presented with umbilical granuloma from December 2018 to May 2020.
Children who received treatment prior to index visit were excluded.
How the Study Was Run
In design terms this was a randomized and pilot study.
The participants were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.
It is described as a pilot, a small early test of whether a larger Copper (Supplement) study would be practical.
The researchers performed a multi centerrandomized controlled trial involving three regional pediatricsurgical units.
Demographic data, compliance in the NaCl group by pill counting method, treatment outcomes, and complications were recorded.
Treatment success was defined as complete lesion resolution.
Partial or no response was considered treatment failure.
Subsequent treatment then reverted to the respective center's routine management.
What Was Measured
The subject headings attached to it are Copper Sulfate, Digestive System Abnormalities, Granuloma, Pilot Projects and Sodium Chloride, Dietary.
Author keywords: Children, Copper sulphate, Randomized controlled trial, Table salt and Umbilical granuloma.
What This Means in Plain Language
The paper is a randomized and pilot study of Copper (Supplement).
Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2022 (Journal of pediatric surgery), a journal based in United States.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.