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Adult attachment style moderates the effect of oxytocin on neural responses to infant emotional faces
Plain-language guide to PMID 34919983 (2022): double-blind randomized controlled trial study of Oxytocin.
Key Facts
- PMID
- 34919983
- Journal
- International journal of psychophysiology : official journal of the International Organization of Psychophysiology
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Ma Y et al. (4 authors)
- DOI
- 10.1016/j.ijpsycho.2021.12.003
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial paper looks at Oxytocin.
The present study aims to examine whether the effects of IN-OT on maternal-related neural responses to infant faces were moderated by participants' attachment style.
Why It Was Studied
Oxytocin (OT) is known for its positive influence on maternal motivation and behavior, however, the effects of intranasal oxytocin (IN-OT) on neural activity during the perception of infant stimuli are often inconsistent.
These discrepancies further reveal the need to take into account individual differences in IN-OT research.
Who Took Part
The age groups tagged for this paper are infants and adults, women only.
The neural responses of participants were assessed during a facial recognition task with joy, neutral, and crying infant faces.
How the Study Was Run
In design terms this was a randomized, double-blind and placebo-controlled study.
Because people in this Oxytocin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Blinding on both sides kept the participants and researchers unaware of who received Oxytocin.
Some participants received a placebo instead of Oxytocin, giving a reference point.
What Was Measured
PubMed files the paper under topics including Emotions, Facial Recognition, Magnetic Resonance Imaging and Oxytocin.
The authors tagged it with the keywords Attachment styles, Infant emotional faces, Maternal empathy and fMRI.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Oxytocin.
The publication is from 2022 (International journal of psychophysiology : official journal of the International Organization of Psychophysiology), a journal based in Netherlands.
More context: the Oxytocin compound page, all human trials.
Our Notes on the Compound
Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.