Predicting Non-Adherence With Very Low Nicotine Content Cigarettes Among Adults With Serious Mental Illness Who Smoke.

What Was Tested

The paper reports a study of Therapeutic nicotine (patch, non-peptide), published as a randomized controlled trial.

The researchers investigated predictors of biologically assessed non-adherence in participants assigned to VLNC cigarettes (n = 30).

Predictors included subjective responses to VLNC cigarettes, baseline nicotine dependence and dependence motives, and psychiatric symptom severity.

The researchers fit a series of linear models regressing non-adherence metrics onto covariates (gender; menthol preference) and focal predictors.

Why It Was Studied

However, interpretation of such trials is challenged by incomplete adherence to the randomized treatment assignment, as some participants may continue to use commercial cigarettes not provided by the trial.

The current study examined prevalence and predictors of non-adherence among trial participants with serious mental illness (SMI).

Who Took Part

By PubMed's age tags, the people studied were adults.

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Therapeutic nicotine (patch, non-peptide) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

What Was Measured

Topics PubMed links to this paper include Mental Disorders, Nicotine, Prevalence, Smoking, Smoking Cessation and Tobacco Products.

What This Means in Plain Language

The paper is a randomized study of Therapeutic nicotine (patch, non-peptide).

Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2022 (Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco), a journal based in England.

More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.