Effect of Calcium and Vitamin D Supplementation With and Without Collagen Peptides on Volumetric and Areal Bone Mineral Density, Bone Geometry and Bone Turnover in Postmenopausal Women With Osteopenia.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc in the context of osteoporosis and bone density.

In the present randomized prospective study, the researchers examined the effect of calcium, vitamin D with and without CPs supplementation on changes in volumetric bone mineral density (vBMD) and bone geometry assessed by peripheral quantitative computed tomography at the tibia, areal bone mineral density (aBMD) assessed by dual-energy X-ray absorptiometry at the lumbar spine and the hip and bone turnover markers over 12-mo.

The primary endpoint was the change of trabecular bone mineral content (BMC) and vBMD after 12-mo supplementation in Groups A and B.

Who Took Part

PubMed tags the participants as women only.

How the Study Was Run

The researchers set it up as a randomized study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

What Was Measured

In the present randomized prospective study, the researchers examined the effect of calcium, vitamin D with and without CPs supplementation on changes in volumetric bone mineral density (vBMD) and bone geometry assessed by peripheral quantitative computed tomography at the tibia, areal bone mineral density (aBMD) assessed by dual-energy X-ray absorptiometry at the lumbar spine and the hip and bone turnover markers over 12-mo.

The primary endpoint was the change of trabecular bone mineral content (BMC) and vBMD after 12-mo supplementation in Groups A and B.

Topics PubMed links to this paper include Absorptiometry, Photon, Bone Density, Bone Diseases, Metabolic, Bone Remodeling, Calcium, Calcium, Dietary and Cholecalciferol.

The authors tagged it with the keywords Bone turnover, calcium supplement, collagen peptides, osteopenia and pQCT.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in people with osteoporosis and bone density.

The publication is from 2022 (Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Osteoporosis and bone density research.