Changes of Endothelin-1 and Calcitonin Gene-Related Peptide Concentrations in Patients with Cervical Radiculopathy after Wrist-Ankle Acupuncture-Moxibustion and Hot Compression with Chinese Herbal Medicine

What Was Tested

Researchers studied Endothelin-1 and CGRP (Calcitonin Gene-Related Peptide) in this randomized controlled trial publication.

This study aimed at investigating the effects of wrist-ankle acupuncture-moxibustion and hot compression with Chinese herbal medicine on pain symptoms, endothelin-1 (ET-1), and calcitonin gene-related peptide (CGRP) concentrations of patients with cervical radiculopathy (CR).

Who Took Part

The study group was 82 patients.

A total of 82 patients with CR were randomly divided into the study group and control group, with 41 cases in each group.

The control group was treated with standard treatment.

How the Study Was Run

The researchers set it up as a randomized study.

The patients were allocated by chance, so the Endothelin-1 group and the comparison group should start out alike.

In addition to standard treatment, the study group was additionally treated with wrist-ankle acupuncture-moxibustion and hot compression with Chinese herbal medicine.

The ET-1 and CGRP concentrations in the plasma were measured by the radioimmunoassay method.

What Was Measured

PubMed files the paper under topics including Acupuncture Points, Acupuncture Therapy, Ankle, Calcitonin Gene-Related Peptide, Drugs, Chinese Herbal, Endothelin-1 and Moxibustion.

What This Means in Plain Language

The paper is a randomized study of Endothelin-1 and CGRP (Calcitonin Gene-Related Peptide) in 82 patients.

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2021 (Genetics research), a journal based in England.

More context: the Endothelin-1 compound page and the CGRP (Calcitonin Gene-Related Peptide) compound page, all human trials.