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Effects of high dairy protein intake and vitamin D supplementation on body composition and cardiometabolic markers in 6-8-y-old children-the D-pro trial.

Plain-language guide to PMID 35015806 (2022): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
35015806
Journal
The American journal of clinical nutrition
Year
2022
Study type
Randomized Controlled Trial
Authors
Thams L et al. (6 authors)
DOI
10.1093/ajcn/nqab424
Registered trial
NCT03956732

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The researchers investigated combined and separate effects of high dairy protein intake and vitamin D on body composition and cardiometabolic markers in children.

Why It Was Studied

Dairy protein and vitamin D can affect body composition and cardiometabolic markers, yet evidence among well-nourished children is sparse.

Who Took Part

By PubMed's age tags, the people studied were children.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

The researchers measured body composition (by DXA), blood pressure, and fasting blood glucose, insulin, C-peptide, and lipids.

What Was Measured

The subject headings attached to it are Blood Glucose, Body Composition, Cardiovascular Diseases, Cholecalciferol, Dietary Supplements, Vitamin D and Vitamin D Deficiency.

The authors tagged it with the keywords BMI, DXA, FFMI, FMI, blood lipids and cholesterol.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 11 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2022 (The American journal of clinical nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.