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The effect of preoperative oral magnesium oxide on the severity of postoperative pain among women undergoing hysterectomy.
Plain-language guide to PMID 35022952 (2022): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 64 patients.
Key Facts
- PMID
- 35022952
- Journal
- Irish journal of medical science
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Hashemian M et al. (5 authors)
- DOI
- 10.1007/s11845-021-02905-8
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
The aim of study was to compare the pre-emptive analgesic effects of oral magnesium oxide and naproxen for hysterectomy surgery.
Who Took Part
The study group was 64 patients.
PubMed tags the participants as women only.
This study evaluated all patients who were candidates for hysterectomy in 2 months.
The 64 patients were randomly divided into two groups using a random allocation sequence.
How the Study Was Run
The design is described as randomized and double-blind.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.
The severity of postoperative pain is assumed as a primary outcome which is evaluated using the visual analogue scale (VAS).
What Was Measured
Topics PubMed links to this paper include Magnesium Oxide, Naproxen, Postoperative Pain, Hysterectomy and Analgesics.
Author keywords: Iran and Oral magnesuim oxide.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 64 patients.
The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2022 (Irish journal of medical science), a journal based in Ireland.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.