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The effect of intra-vaginal oxytocin on sexual function in breastfeeding mothers: a randomized triple-blind placebo-controlled trial
Plain-language guide to PMID 35065634 (2022): placebo-controlled randomized controlled trial study of Oxytocin in 64 women, sexual function & libido (women and men).
Key Facts
- PMID
- 35065634
- Journal
- BMC pregnancy and childbirth
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Mesbahi A et al. (4 authors)
- DOI
- 10.1186/s12884-022-04384-w
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Oxytocin in the context of sexual function & libido (women and men), published as a randomized controlled trial.
ANCOVA test was used to compare post-intervention mean score of the groups, adjusted for the baseline values.
Why It Was Studied
The Iranian Registry of Clinical Trials (IRCT), code: IRCT20120718010324N55 , Date of registration: 27/05/2020, URL: https://en.irct.ir/user/trial/44986/view .
Who Took Part
According to the abstract, 64 women were involved.
By PubMed's age tags, the people studied were adults, women only.
This randomized triple-blind controlled trial was conducted on 64 breastfeeding women who referred to health centers in the city of Tabriz, Iran, in 2020-21.
Standard questionnaires of Female Sexual Function Index (FSFI), Edinburgh Postpartum Depression Scale (EPDS) and Sexual satisfaction scale for women (SSSW) were completed at baseline and 8 weeks after intervention.
How the Study Was Run
In design terms this was a randomized and placebo-controlled study.
Random assignment meant chance, not the researchers, decided who got Oxytocin and who got the comparison, which limits bias.
The comparison arm used a placebo, so changes seen with Oxytocin could be set against what happens without it.
What Was Measured
PubMed files the paper under topics including Breast Feeding, Depression, Mothers, Orgasm, Oxytocin, Sexual Dysfunction, Physiological and Surveys and Questionnaires.
Author keywords: Breastfeeding mothers, Intravaginal Oxytocin, Postpartum and Sexual function.
What This Means in Plain Language
The paper is a randomized and placebo-controlled study of Oxytocin in 64 women in people with sexual function & libido (women and men).
Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2022 (BMC pregnancy and childbirth), a journal based in England.
More context: the Oxytocin compound page, Sexual function & libido (women and men) research.
Our Notes on the Compound
Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.