Vitamin D, vitamin D-binding protein, free vitamin D and COVID-19 mortality in hospitalized patients.

What Was Tested

This observational study looks at Vitamin D, K2, Magnesium and Zinc.

The researchers aimed to examine the relationship between vitamin D status and mortality from COVID-19.

Why It Was Studied

Because of this, measurements of unbound ("free") and albumin-bound ("bioavailable") 25(OH)D have been proposed.

Who Took Part

The study group was 19 patients.

By PubMed's age tags, the people studied were older adults, both men and women.

How the Study Was Run

Clinical data, including age, ethnicity, and comorbidities, were extracted from case notes.

Serum 25(OH)D, DBP, and albumin concentrations were measured.

Free and bioavailable 25(OH)D were calculated.

Relationships between total, free, and bioavailable 25(OH)D and 28-day mortality were analyzed by logistic regression.

What Was Measured

Because of this, measurements of unbound ("free") and albumin-bound ("bioavailable") 25(OH)D have been proposed.

PubMed files the paper under topics including Albumins, COVID-19, Vitamin D, Vitamin D Deficiency, Vitamin D-Binding Protein and Vitamins.

The authors tagged it with the keywords COVID-19 mortality, bioavailable vitamin D, free vitamin D and vitamin D–binding protein.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 19 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2022 (The American journal of clinical nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.