Evaluation of Autofluorescence in Identifying Parathyroid Glands by Measuring Parathyroid Hormone in Fine-Needle Biopsy Washings

What Was Tested

The paper reports a study of Parathyroid Hormone (PTH 1-84), published as a clinical trial.

Near-infrared autofluorescence imaging has potentially great value for assisting endocrine surgeons in identifying parathyroid glands and may dramatically change the surgical strategy of endocrine surgeons in thyroid surgery.

This study is designed to objectively evaluate the role of near-infrared autofluorescence imaging in identifying parathyroid glands during thyroid surgery by measuring intraoperative parathyroid hormone in fine-needle aspiration biopsy washings.

Who Took Part

Patients undergoing total thyroidectomy with or without neck lymph node dissection were consecutively included.

How the Study Was Run

This study was conducted at a tertiary referral teaching hospital in China from February 2020 to June 2020.

The surgeon used near-infrared autofluorescence imaging to identify parathyroid glands during thyroid surgery and confirmed suspicious parathyroid tissues by measuring their intraoperative parathyroid hormone.

Nanocarbon was injected into the thyroid gland if the thyroid autofluorescence intensity was too strong.

The sensitivity and accuracy of near-infrared autofluorescence imaging and vision for identifying parathyroid glands, and the difference in autofluorescence intensity in various tissues were the main outcomes.

What Was Measured

This study is designed to objectively evaluate the role of near-infrared autofluorescence imaging in identifying parathyroid glands during thyroid surgery by measuring intraoperative parathyroid hormone in fine-needle aspiration biopsy washings.

The subject headings attached to it are Biopsy, Fine-Needle, Optical Imaging, Parathyroid Glands, Parathyroid Hormone and Thyroidectomy.

The authors tagged it with the keywords autofluorescence, lymph node, nanocarbon and thyroid surgery.

What This Means in Plain Language

This is a clinical trial of Parathyroid Hormone (PTH 1-84).

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2021 (Frontiers in endocrinology), a journal based in Switzerland.

More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.