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The Clinical Value of High-Quality Nursing in Concurrent Radiotherapy and Chemotherapy after Glioma Surgery and Its Influence on the Stress Indicators Cor, ACTH, and CRP
Plain-language guide to PMID 35126950 (2022): randomized controlled trial study of ACTH (Corticotropin) in 94 patients.
Key Facts
- PMID
- 35126950
- Journal
- Journal of healthcare engineering
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Fang H et al. (4 authors)
- DOI
- 10.1155/2022/8335400
What This Study Did, in Plain Language
What Was Tested
Researchers studied ACTH (Corticotropin) in this randomized controlled trial publication.
The purpose of this study is to explore the clinical value of high-quality nursing in concurrent radiotherapy and chemotherapy after glioma surgery and its influence on the stress indicators such as cortisol (Cor), adrenocorticotrophic hormone (ACTH), and C-reactive protein (CRP).
Who Took Part
The study group was 94 patients.
A total of 94 glioma patients diagnosed and treated in their hospital were randomly divided into a research group and a control group, with 47 cases in each group.
Both groups of patients were given concurrent radiotherapy and chemotherapy.
How the Study Was Run
The design is described as randomized.
Random assignment meant chance, not the researchers, decided who got ACTH (Corticotropin) and who got the comparison, which limits bias.
On this basis, patients in the control group were given basic care, while patients in the research group were given a combination of basic care and high-quality care.
The nursing satisfaction and adverse reactions of the two groups were compared.
The pain degree and the levels of stress indicators Cor, ACTH, and CRP at different time points were compared between the two groups.
The sleep quality, bad mood, and quality of life before and after nursing were compared between the two groups.
What Was Measured
Topics PubMed links to this paper include Adrenocorticotropic Hormone, C-Reactive Protein, Dizziness, Glioma, Hydrocortisone, Leukopenia and Nausea.
What This Means in Plain Language
The paper is a randomized study of ACTH (Corticotropin) in 94 patients.
The abstract goes on to report its results in about 15 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2022 (Journal of healthcare engineering), a journal based in England.
More context: the ACTH (Corticotropin) compound page, all human trials.
Our Notes on the Compound
ACTH (Corticotropin): The 39-amino-acid pituitary hormone that drives cortisol production; given as repository corticotropin (Acthar Gel).
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.