← Human Trials & Peer-Reviewed Studies

Magnesium-Based Trigger Point Infiltrations Versus Local Anaesthetic Infiltrations in Chronic Pelvic Myofascial Pain: A Randomized, Double-Blind, Controlled Study.

Plain-language guide to PMID 35339694 (2022): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc, chronic pain: fibromyalgia & crps.

Key Facts

PMID
35339694
Journal
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
Year
2022
Study type
Randomized Controlled Trial
Authors
Leitch J et al. (6 authors)
DOI
10.1016/j.jogc.2022.02.129
Registered trial
NCT02728037

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in the context of chronic pain: fibromyalgia & crps in this randomized controlled trial publication.

Who Took Part

PubMed tags the participants as women only.

The researchers compared a novel magnesium-based infiltration formulation with lidocaine infiltration of trigger points and with a control group of participants who were waitlisted for a chronic pain clinic.

Treatment groups completed a 12-week program that included 8 trigger point injection treatments and 9 visits during which pain scores were recorded and questionnaires administered.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

The primary outcome measure was change in mean pain score between baseline and the final visit.

Secondary outcomes included pain with function scores, scores on the World Health Organization Quality of Life questionnaire, procedural pain, concomitant medication use, and complications.

What Was Measured

PubMed files the paper under topics including Anesthetics, Local, Chronic Pain, Lidocaine, Magnesium, Myofascial Pain Syndromes, Pelvic Pain and Quality of Life.

Author keywords: musculoskeletal pain and trigger points.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in people with chronic pain: fibromyalgia & crps.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2022 (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC), a journal based in Netherlands.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Chronic pain: fibromyalgia & CRPS research.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.