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Effects of oxytocin and vasopressin administration on human fathers' sensitive and challenging parenting: A randomized within-subject controlled trial

Plain-language guide to PMID 35430502 (2022): double-blind randomized controlled trial study of Oxytocin and Vasopressin.

Key Facts

PMID
35430502
Journal
Hormones and behavior
Year
2022
Study type
Randomized Controlled Trial
Authors
Witte AM et al. (6 authors)
DOI
10.1016/j.yhbeh.2022.105175

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Oxytocin and Vasopressin, published as a randomized controlled trial.

This randomized, double-blind, placebo-controlled within-subject study examined the effects of intranasal administration of oxytocin and vasopressin on fathers' sensitive and challenging parenting behaviors.

Furthermore, the researchers examined the moderating role of fathers' early childhood experiences.

Who Took Part

The age groups tagged for this paper are infants, men only.

All fathers were assigned to each of the three experimental sessions (oxytocin, vasopressin, and placebo), on three separate days, with random order and intervening periods of one to two weeks.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Because people in this Oxytocin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the participants nor the staff measuring them knew who was on Oxytocin, so expectations could not easily colour the readings.

A placebo (an inactive look-alike) gave the Oxytocin group a baseline to be compared against.

What Was Measured

The subject headings attached to it are Adverse Childhood Experiences, Fathers, Oxytocin, Parenting, Paternal Behavior, Role and Vasopressins.

Author keywords: Challenging parenting behavior, Early childhood adversity and Sensitivity.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Oxytocin and Vasopressin.

The publication is from 2022 (Hormones and behavior), a journal based in United States.

More context: the Oxytocin compound page and the Vasopressin compound page, all human trials.

Our Notes on the Compounds

Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.

Vasopressin: A 9-amino-acid hormone (antidiuretic hormone) that controls water balance and blood vessel tone; used in septic shock.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.