Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Postoperative Pain Relief and Decrease Opioid Consumption: A Prospective Randomized Controlled Trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Adequate pain management is a critical component of facilitating same-day discharge for total knee arthroplasty (TKA).

The objective of this study was to investigate the impact of adding magnesium to local anesthetic in ACB on postoperative pain, opioid consumption, nausea, and overall patient satisfaction.

Who Took Part

The abstract describes 119 adults taking part.

PubMed indexes the participants as adults.

A sample of 119 adults undergoing elective unilateral TKA were included.

Patients were randomly assigned to receive ACB with magnesium and bupivacaine (n=56) or with bupivacaine only (n=63).

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Primary outcomes were total opioid consumption in the first 48 hours after surgery and pain scores.

Secondary outcomes were the incidence of nausea in the first 48 hours after surgery and total overall satisfaction.

What Was Measured

Topics PubMed links to this paper include Analgesics, Opioid, Anesthetics, Local, Arthroplasty, Replacement, Knee, Bupivacaine, Magnesium, Nausea and Nerve Block.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 119 adults.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2022 (The Clinical journal of pain), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.