Vitamin D and COVID-19 Severity in Hospitalized Older Patients: Potential Benefit of Prehospital Vitamin D Supplementation.

What Was Tested

This observational study looks at Vitamin D, K2, Magnesium and Zinc.

This study aimed to assess the relationships between vitamin D (VitD) status and supplementation and coronavirus disease 2019 (COVID-19) severity in older adults (average age of 78 years) hospitalized for COVID-19.

Why It Was Studied

Studies involving the associations between vitamin D supplementation taken before the onset of COVID-19 infection and the clinical outcomes are still scarce and this issue remains controversial.

The researchers conducted an observational retrospective cohort study with 228 older hospitalized patients during the first wave of the COVID-19 pandemic.

Who Took Part

According to the abstract, 228 patients were involved.

The age groups tagged for this paper are older adults, men only.

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

What Was Measured

Studies involving the associations between vitamin D supplementation taken before the onset of COVID-19 infection and the clinical outcomes are still scarce and this issue remains controversial.

The outcomes were in-hospital mortality secondary to COVID-19 or critically severe COVID-19.

PubMed files the paper under topics including COVID-19, Dietary Supplements, Emergency Medical Services, Pandemics, SARS-CoV-2, Vitamin D and Vitamin D Deficiency.

The authors tagged it with the keywords elderly, mortality and supplementation.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 228 patients.

The publication is from 2022 (Nutrients), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.