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Early pregnancy vitamin D status is associated with blood pressure in children: an Odense Child Cohort study.

Plain-language guide to PMID 35511609 (2022): observational study of Vitamin D, K2, Magnesium and Zinc, low blood pressure and orthostatic hypotension.

Key Facts

PMID
35511609
Journal
The American journal of clinical nutrition
Year
2022
Study type
Observational Study
Authors
Pedersen JN et al. (7 authors)
DOI
10.1093/ajcn/nqac118

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in the context of low blood pressure and orthostatic hypotension in this observational study publication.

Blood pressure in childhood tracks into later life.

Who Took Part

PubMed indexes the participants as children and adults, both men and women.

In a prospective observational study within the population-based Odense Child Cohort (OCC), the researchers examined serum 25-hydroxyvitamin D2+3 [s-25(OH)D] in early and late pregnancy, cord blood, and at 5 y age, and the associations with systolic and diastolic blood pressure (SBP/DBP) in the 5-y-old children (n = 1,677).

How the Study Was Run

Multiple regression models were adjusted for maternal country of origin, parity, smoking during pregnancy, 5-y height, and weight.

Two-stage mixed effect modeling was performed, integrating all s-25(OH)D data from pregnancy and cord blood.

What Was Measured

The subject headings attached to it are Blood Pressure, Cohort Studies, Fetal Blood, Vitamin D, Vitamin D Deficiency and Vitamins.

The authors tagged it with the keywords 25(OH)D, cardio-metabolic health, children, fetal programming, pregnancy and vitamin D status.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in people with low blood pressure and orthostatic hypotension.

Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2022 (The American journal of clinical nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Low blood pressure and orthostatic hypotension research.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.