Effectiveness of three Vitamin D dosing protocols on raising and maintaining blood serum levels of 25-hydroxyvitamin D over a three-month period: a randomized, prospective study.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

The primary outcome was to determine which protocol could achieve and maintain therapeutic levels of total 25-hydroxyvitamin D over the course of three months.

Their secondary outcome was to monitor for negative side effects.

Why It Was Studied

Vitamin D has gained attention in the medical community due to its critical role in calcium homeostasis and overall bone health.

Who Took Part

According to the abstract, 2017, patients were involved.

How the Study Was Run

In design terms this was a randomized study.

The patients were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Baseline serum levels were drawn followed by interval levels at week 2, 6 and 12.

What Was Measured

Topics PubMed links to this paper include Ergocalciferols, Serum, Vitamin D, Vitamin D Deficiency and Vitamins.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 2017, patients.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2023 (European journal of orthopaedic surgery & traumatology : orthopedie traumatologie), a journal based in France.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.