Maternal vitamin D status in pregnancy and molar incisor hypomineralisation and hypomineralised second primary molars in the offspring at 7-9 years of age: a longitudinal study.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

The study aimed to investigate associations between maternal vitamin D status during pregnancy and molar incisor hypomineralisation (MIH) and hypomineralised second primary molars (HSPM) among children.

Mothers were initially recruited in a randomised controlled trial to assess a pregnancy exercise programme.

Who Took Part

PubMed indexes the participants as children, women only.

The study had a longitudinal design using prospectively collected data from 176 mother and child pairs.

Along with the 7-year follow-up, the researchers invited the children to a dental examination.

How the Study Was Run

In design terms this was a randomized study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Negative binomial hurdle models were used to analyse potential associations between the exposure variables and MIH or HSPM.

The models were adjusted for potential confounders.

What Was Measured

PubMed files the paper under topics including Dental Enamel Hypoplasia, Longitudinal Studies, Molar, Prevalence and Vitamin D.

Author keywords: Dental caries, Enamel hypomineralisation, HSPM, MIH and Pregnancy.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2022 (European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.