The effect of calcium and vitamin D supplements on blood pressure in postmenopausal women: myth or reality?

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc in the context of low blood pressure and orthostatic hypotension.

Hypertension is a highly prevalent disease with serious cardiovascular and renal complications.

However, the results to date remain controversial.

Who Took Part

The study group was 98 women.

PubMed tags the participants as women only.

How the Study Was Run

The design is described as randomized and double-blind.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Blinding on both sides kept the women and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

What Was Measured

In this study, the researchers assessed the effect of calcium and vitamin D supplementation on the blood pressure of postmenopausal women with hypertension as a population group in which the use of calcium supplements is prevalent.

Topics PubMed links to this paper include Blood Pressure, Blood Pressure Monitoring, Ambulatory, Calcium, Dietary Supplements, Hypertension, Postmenopause and Vitamin D.

The authors tagged it with the keywords Ambulatory blood pressure monitoring, Calcium; Vitamin D and Postmenopausal women.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 98 women in people with low blood pressure and orthostatic hypotension.

The publication is from 2022 (Hypertension research : official journal of the Japanese Society of Hypertension), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Low blood pressure and orthostatic hypotension research.