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The level of vitamin D in follicular fluid and ovarian reserve in an in vitro fertilization program: A pilot study.
Plain-language guide to PMID 35619572 (2022): pilot observational study of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 35619572
- Journal
- Science progress
- Year
- 2022
- Study type
- Observational Study
- Authors
- Han JY et al. (4 authors)
- DOI
- 10.1177/00368504221103782
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as an observational study.
The aim of this study is to evaluate the association between FF vitamin D levels and baseline anti-Müllerian hormone (AMH) / ART outcomes.
Multivariable linear regression analysis was used to assess the association between baseline AMH and FF vitamin D levels with adjustment for basal FSH and serum vitamin D levels.
Why It Was Studied
The level of vitamin D in follicular fluid (FF) according to the ovarian reserve has never been investigated, and the effect of FF vitamin D on the outcome of assisted reproductive technology (ART) remains controversial.
Who Took Part
PubMed tags the participants as women only.
Forty-seven patients who underwent controlled ovarian stimulation at the fertility clinic of an academic tertiary care center were enrolled for a prospective observational study.
How the Study Was Run
The researchers set it up as a pilot study.
It is described as a pilot, a small early test of whether a larger Vitamin D, K2, Magnesium and Zinc study would be practical.
FF was collected from the first aspirated leading follicle of each ovary and assayed by an enzyme-linked immunosorbent assay.
What Was Measured
The level of vitamin D in follicular fluid (FF) according to the ovarian reserve has never been investigated, and the effect of FF vitamin D on the outcome of assisted reproductive technology (ART) remains controversial.
PubMed files the paper under topics including Anti-Mullerian Hormone, Fertilization in Vitro, Follicular Fluid, Ovarian Reserve, Pilot Projects, Vitamin D and Vitamins.
The authors tagged it with the keywords in vitro fertilization.
What This Means in Plain Language
The paper is a pilot study of Vitamin D, K2, Magnesium and Zinc.
The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2022 (Science progress), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.