← Human Trials & Peer-Reviewed Studies
Nitric-Oxide-Inducing Factors on Vitamin D Changes in Older People Susceptible to Suffer from Sarcopenia.
Plain-language guide to PMID 35627475 (2022): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 35627475
- Journal
- International journal of environmental research and public health
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Córdova A et al. (6 authors)
- DOI
- 10.3390/ijerph19105938
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
Calcium and magnesium, together with vitamin D and the hormones testosterone and cortisol, are key elements in muscle function, to maintain physical fitness.
This study aims to analyze if supplementation with NO precursors (L-arginine, L-citrulline and beetroot extract) modulates the circulating levels of calcium, magnesium, vitamin D and steroid hormones in elders.
Who Took Part
The age groups tagged for this paper are older adults.
How the Study Was Run
The researchers set it up as a randomized and placebo-controlled study.
The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.
Physical capacity was assessed through the following tests: (a) distance covered in 6 min by walking (endurance indicator); (b) hand grip (upper-body strength indicator); (c) time to cover 4 m by walking (speed indicator); and (d) time to perform five full squats (lower-body strength indicator).
What Was Measured
Calcium and magnesium, together with vitamin D and the hormones testosterone and cortisol, are key elements in muscle function, to maintain physical fitness.
This study aims to analyze if supplementation with NO precursors (L-arginine, L-citrulline and beetroot extract) modulates the circulating levels of calcium, magnesium, vitamin D and steroid hormones in elders.
PubMed files the paper under topics including Arginine, Calcium, Calcium, Dietary, Hand Strength, Hormones, Magnesium and Nitric Oxide.
The authors tagged it with the keywords citrulline and nitrate.
What This Means in Plain Language
The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.
The publication is from 2022 (International journal of environmental research and public health), a journal based in Switzerland.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.