← Human Trials & Peer-Reviewed Studies

Vitamin D supplementation and increased dairy protein intake do not affect muscle strength or physical function in healthy 6-8-year-old children: the D-pro randomized trial.

Plain-language guide to PMID 35643873 (2022): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
35643873
Journal
European journal of nutrition
Year
2022
Study type
Randomized Controlled Trial
Authors
Thams L et al. (7 authors)
DOI
10.1007/s00394-022-02912-0
Registered trial
NCT03956732

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Who Took Part

The age groups tagged for this paper are children, both men and women.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

The researchers measured maximal isometric handgrip and leg press strength, and physical function by jump tests and a 30 s sit-to-stand test.

Physical activity was measured by 7-day accelerometry.

What Was Measured

PubMed files the paper under topics including Cholecalciferol, Dietary Supplements, Hand Strength, Milk Proteins, Muscle Strength, Sex Factors and Vitamin D Deficiency.

Author keywords: Muscle function, Pediatric and Physical performance.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2022 (European journal of nutrition), a journal based in Germany.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.