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Vitamin D supplementation and increased dairy protein intake do not affect muscle strength or physical function in healthy 6-8-year-old children: the D-pro randomized trial.
Plain-language guide to PMID 35643873 (2022): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 35643873
- Journal
- European journal of nutrition
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Thams L et al. (7 authors)
- DOI
- 10.1007/s00394-022-02912-0
- Registered trial
- NCT03956732
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
Who Took Part
The age groups tagged for this paper are children, both men and women.
How the Study Was Run
The researchers set it up as a randomized, double-blind and placebo-controlled study.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.
The researchers measured maximal isometric handgrip and leg press strength, and physical function by jump tests and a 30 s sit-to-stand test.
Physical activity was measured by 7-day accelerometry.
What Was Measured
PubMed files the paper under topics including Cholecalciferol, Dietary Supplements, Hand Strength, Milk Proteins, Muscle Strength, Sex Factors and Vitamin D Deficiency.
Author keywords: Muscle function, Pediatric and Physical performance.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.
Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2022 (European journal of nutrition), a journal based in Germany.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.