Comparison of the Effect of Anesthetic Agents on Blood Levels of Parathyroid Hormone and Ionized Calcium: A Prospective Randomized Controlled Trial

What Was Tested

Researchers studied Parathyroid Hormone (PTH 1-84) in this randomized controlled trial publication.

The aim of this randomized control trial is to compare the effect of anesthetic agents on blood levels of parathyroid hormone and ionized calcium. 77 American Society of Anesthesiologists I-II patients who would undergo laparoscopic cholecystectomy were enrolled into this prospective study and randomized into 3 groups with sealed envelope technique as Group S: sevoflurane, Group D: desflurane, and Group TIVA: total intravenous anesthesia.

Why It Was Studied

The first blood sample was used to check the baseline blood levels of parathyroid hormone and ionized calcium.

At the 30th minute of anesthesia and at the 1st hour of end of anesthesia, 2nd and 3rd blood samples, respectively, were used to check the blood levels of PTH and Ca.

How the Study Was Run

The design is described as randomized.

The participants were allocated by chance, so the Parathyroid Hormone (PTH 1-84) group and the comparison group should start out alike.

What Was Measured

The first blood sample was used to check the baseline blood levels of parathyroid hormone and ionized calcium.

At the 30th minute of anesthesia and at the 1st hour of end of anesthesia, 2nd and 3rd blood samples, respectively, were used to check the blood levels of PTH and Ca.

PubMed files the paper under topics including Anesthesia Recovery Period, Anesthetics, Intravenous, Calcium, Desflurane, Parathyroid Hormone and Sevoflurane.

What This Means in Plain Language

The paper is a randomized study of Parathyroid Hormone (PTH 1-84).

The publication is from 2022 (International journal of clinical practice), a journal based in United States.

More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.