Blood Glucose Response of a Low-Carbohydrate Oral Nutritional Supplement with Isomaltulose and Soluble Dietary Fiber in Individuals with Prediabetes: A Randomized, Single-Blind Crossover Trial.

What Was Tested

Researchers studied Copper (Supplement) in this randomized controlled trial publication.

This study aimed to evaluate the impact of LC-ONS on blood glucose levels after ingestion in individuals with prediabetes.

Why It Was Studied

A high-energy-type oral dietary supplement (ONS), with a low proportion of available carbohydrate (LC-ONS), which contains a slowly digestible carbohydrate, isomaltulose, and is fortified with soluble dietary fiber, was newly developed for individuals with diabetes or prediabetes.

A single-blind, randomized crossover clinical trial was performed on 20 individuals with prediabetes.

Who Took Part

The abstract describes 20 individuals taking part.

How the Study Was Run

The design is described as randomized, single-blind and crossover.

The individuals were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.

In this single-blind Copper (Supplement) study one party knew the assignments and the other did not.

In the crossover set-up each of the individuals took both Copper (Supplement) and the comparison in turn, acting as their own control.

What Was Measured

The subject headings attached to it are Blood Glucose, Dietary Fiber, Glucose, Insulin, Isomaltose, Postprandial Period and Prediabetic State.

Author keywords: isomaltulose, oral nutritional supplement and prediabetes.

What This Means in Plain Language

The paper is a randomized, single-blind and crossover study of Copper (Supplement) in 20 individuals.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 2022 (Nutrients), a journal based in Switzerland.

More context: the Copper (Supplement) compound page, all human trials.