Vitamin D status in breast cancer cases following chemotherapy: A pre and post observational study in a tertiary hospital in Yogyakarta, Indonesia.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this observational study publication.

To observe pre- and post-treatment vitamin D level and its association with treatment and concomitant factors in breast cancer patients treated with chemotherapy.

Paired t-test was used to evaluate changes in post-treatment vitamin D concentration.

Who Took Part

The abstract describes 136 subjects taking part.

PubMed tags the participants as women only.

The researchers performed a pre-post observational analysis that nested in an ongoing prospective cohort study of breast cancer patients at Dr.

Sardjito General Hospital, Yogyakarta, Indonesia. 136 subjects were recruited from the main study.

How the Study Was Run

Information on subjects' socio-demographic characteristics clinical status, and tumour profile was assessed at baseline.

Number of chemotherapy cycles and chemotherapy-induced nausea vomiting (CINV) were also recorded.

Vitamin D concentration was measured using ELISA methods at baseline and post-treatment.

Vitamin D level of <20 ng/ml and <12 ng/ml were defined as deficiency and severe deficiency.

Correlation between socio-demographic and clinical profile with baseline vitamin D was tested using Spearman correlation.

What Was Measured

The subject headings attached to it are Breast Neoplasms, Indonesia, Nausea, Tertiary Care Centers, Vitamin D, Vitamin D Deficiency and Vitamins.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 136 subjects.

Results are reported in around 9 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2022 (PloS one), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.