Correlation Between Vitamin B12 Deficiency and Autoimmune Thyroid Diseases.

What Was Tested

Researchers studied Cyanocobalamin (Vitamin B12) in this observational study publication.

The aim of this study was therefore to investigate the correlation between vitamin B12 deficiency and AITD.

Why It Was Studied

Autoimmune thyroid diseases (AITD) are the most prevalent organ-specific autoimmune disorders.

Vitamin B12 plays an important role in the proper functioning of the immune system.

Who Took Part

The study group was 306 patients.

PubMed tags the participants as both men and women.

Patients were divided into groups: with and without vitamin B12 deficiency, and with and without AITD.

How the Study Was Run

Differences between groups were evaluated by Fisher's exact test for qualitative variables and by Student's t-test for quantitative variables.

Correlations for quantitative factors were determined by the Pearson correlation coefficient and for qualitative factors by Spearman correlation analysis.

The sensitivity and specificity of vitamin B12 deficiency for AITD were calculated by ROC analysis.

What Was Measured

Topics PubMed links to this paper include Vitamin B 12 Deficiency, Hashimoto Disease, Vitamin B 12 and Thyroiditis, Autoimmune.

The authors tagged it with the keywords AITD, B12 vitamin, correlation and immune system.

What This Means in Plain Language

This is an observational study of Cyanocobalamin (Vitamin B12) in 306 patients.

With several hundred people or more, it is a fairly large study for this kind of research.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2023 (Endocrine, metabolic & immune disorders drug targets), a journal based in United Arab Emirates.

More context: the Cyanocobalamin (Vitamin B12) compound page, all human trials.