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Preterm Infants on Early Solid Foods and Vitamin D Status in the First Year of Life-A Secondary Outcome Analysis of a Randomized Controlled Trial.

Plain-language guide to PMID 35956281 (2022): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 177 infants.

Key Facts

PMID
35956281
Journal
Nutrients
Year
2022
Study type
Randomized Controlled Trial
Authors
Thanhaeuser M et al. (13 authors)
DOI
10.3390/nu14153105

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

The aim of this study was to examine whether two timepoints for the introduction of solid foods in preterm infants have an impact on vitamin D status in the first year of life.

Why It Was Studied

Preterm birth places infants at high risk for mineral and micronutrient deficiencies important for bone health.

This is a secondary outcome analysis of a prospective, randomized trial on very low birth weight (VLBW) infants, randomized to an early (10-12th week corrected age) or a late (16-18th week corrected age) complementary-feeding group.

Who Took Part

The study group was 177 infants.

By PubMed's age tags, the people studied were infants, women only.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Vitamin D status was assessed by blood samples taken at 6 weeks, 6, and 12 months corrected age.

What Was Measured

This is a secondary outcome analysis of a prospective, randomized trial on very low birth weight (VLBW) infants, randomized to an early (10-12th week corrected age) or a late (16-18th week corrected age) complementary-feeding group.

PubMed files the paper under topics including Infant, Premature, Premature Birth, Vitamin D, Vitamin D Deficiency and Vitamins.

Author keywords: preterm infant, solid foods, vitamin D intake and vitamin D status.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 177 infants.

The publication is from 2022 (Nutrients), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.