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[Effect mechanism of pricking and cupping therapy combined with Chinese herbal wet compress in treatment of herpes zoster based on Th1/Th2 imbalance and serum substance P]
Plain-language guide to PMID 36153457 (2022): randomized controlled trial study of Substance P.
Key Facts
- PMID
- 36153457
- Journal
- Zhen ci yan jiu = Acupuncture research
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Wang L et al. (7 authors)
- DOI
- 10.13702/j.1000-0607.20210893
What This Study Did, in Plain Language
What Was Tested
Researchers studied Substance P in this randomized controlled trial publication.
Who Took Part
The patients of herpes zoster at acute stage were randomly divided into a treatment group (58 cases), a control group No.1 (57 cases), a control group No.2 (58 cases) and a control group No.3 (59 cases).
In the treatment group, the therapeutic regimen was pricking and cupping+Chinese herbal wet compress+basic treatment.
How the Study Was Run
The design is described as randomized.
The participants were allocated by chance, so the Substance P group and the comparison group should start out alike.
In the control group No.1, pricking and cupping + basic treatment were administered.
In the control group No.2, Chinese herbal wet compress+basic treatment were provided.
In the control group No.3, only basic treatment was delivered.
The treatment duration was 9 days in each group.
The score of pain degree, the score of sleep quality and the rehabilitation conditions of pain and herpes were observed in 4 groups.
What Was Measured
PubMed files the paper under topics including China, Cupping Therapy, Herpes Zoster, Interferon-gamma, Interleukin-4, Neuralgia and Substance P.
Author keywords: Chinese herbal wet compress, Interferon gamma, Interleukin 4 and Pricking therapy.
What This Means in Plain Language
The paper is a randomized study of Substance P.
The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2022 (Zhen ci yan jiu = Acupuncture research), a journal based in China.
More context: the Substance P compound page, all human trials.
Our Notes on the Compound
Substance P: An 11-amino-acid neuropeptide involved in pain signaling and inflammation; given in research studies.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.