← Human Trials & Peer-Reviewed Studies

[Effect mechanism of pricking and cupping therapy combined with Chinese herbal wet compress in treatment of herpes zoster based on Th1/Th2 imbalance and serum substance P]

Plain-language guide to PMID 36153457 (2022): randomized controlled trial study of Substance P.

Key Facts

PMID
36153457
Journal
Zhen ci yan jiu = Acupuncture research
Year
2022
Study type
Randomized Controlled Trial
Authors
Wang L et al. (7 authors)
DOI
10.13702/j.1000-0607.20210893

What This Study Did, in Plain Language

What Was Tested

Researchers studied Substance P in this randomized controlled trial publication.

Who Took Part

The patients of herpes zoster at acute stage were randomly divided into a treatment group (58 cases), a control group No.1 (57 cases), a control group No.2 (58 cases) and a control group No.3 (59 cases).

In the treatment group, the therapeutic regimen was pricking and cupping+Chinese herbal wet compress+basic treatment.

How the Study Was Run

The design is described as randomized.

The participants were allocated by chance, so the Substance P group and the comparison group should start out alike.

In the control group No.1, pricking and cupping + basic treatment were administered.

In the control group No.2, Chinese herbal wet compress+basic treatment were provided.

In the control group No.3, only basic treatment was delivered.

The treatment duration was 9 days in each group.

The score of pain degree, the score of sleep quality and the rehabilitation conditions of pain and herpes were observed in 4 groups.

What Was Measured

PubMed files the paper under topics including China, Cupping Therapy, Herpes Zoster, Interferon-gamma, Interleukin-4, Neuralgia and Substance P.

Author keywords: Chinese herbal wet compress, Interferon gamma, Interleukin 4 and Pricking therapy.

What This Means in Plain Language

The paper is a randomized study of Substance P.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2022 (Zhen ci yan jiu = Acupuncture research), a journal based in China.

More context: the Substance P compound page, all human trials.

Our Notes on the Compound

Substance P: An 11-amino-acid neuropeptide involved in pain signaling and inflammation; given in research studies.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.