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Intestinal Calcium Absorption Decreases After Laparoscopic Sleeve Gastrectomy Despite Optimization of Vitamin D Status.
Plain-language guide to PMID 36196648 (2023): observational study of Vitamin D, K2, Magnesium and Zinc in 35 women.
Key Facts
- PMID
- 36196648
- Journal
- The Journal of clinical endocrinology and metabolism
- Year
- 2023
- Study type
- Observational Study
- Authors
- Wu KC et al. (14 authors)
- DOI
- 10.1210/clinem/dgac579
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as an observational study.
The researchers determined the effect of LSG on FCA, while maintaining robust 25-hydroxyvitamin D (25OHD) levels and recommended calcium intake.
Why It Was Studied
While Roux-en-Y gastric bypass is known to impair intestinal fractional calcium absorption (FCA) and negatively affect bone metabolism, LSG's effects on calcium homeostasis and bone health have not been well characterized.
Who Took Part
According to the abstract, 35 women were involved.
PubMed tags the participants as both men and women.
Prospective pre-post observational cohort study of 35 women and men with severe obesity undergoing LSG.
What Was Measured
While Roux-en-Y gastric bypass is known to impair intestinal fractional calcium absorption (FCA) and negatively affect bone metabolism, LSG's effects on calcium homeostasis and bone health have not been well characterized.
PubMed files the paper under topics including Calcium, Vitamin D, Gastric Bypass, Vitamins, Bone Density, Obesity, Morbid and Calcium, Dietary.
The authors tagged it with the keywords bariatric surgery, bone mineral density, bone turnover markers, calcium absorption and laparoscopic sleeve gastrectomy.
What This Means in Plain Language
This is an observational study of Vitamin D, K2, Magnesium and Zinc in 35 women.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2023 (The Journal of clinical endocrinology and metabolism), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.