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Effect of vitamin D supplementation on the severity of stress urinary incontinence in premenopausal women with vitamin D insufficiency: a randomized controlled clinical trial.
Plain-language guide to PMID 36333692 (2022): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 60 women.
Key Facts
- PMID
- 36333692
- Journal
- BMC women's health
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Shahraki SK et al. (6 authors)
- DOI
- 10.1186/s12905-022-02024-1
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
The International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-SF) was utilized to assess SUI severity before and after the intervention.
Why It Was Studied
Urinary incontinence, especially stress urinary incontinence (SUI), is one of the problems experienced by premenopausal women.
Given the role of vitamin D in enhancing muscle strength and function, this study explored the effect of vitamin D3 supplementation on SUI in premenopausal women.
Who Took Part
The study group was 60 women.
PubMed tags the participants as women only.
A randomized controlled trial was performed with 60 premenopausal women referring to Kerman gynecological clinic in 2020 and 2021.
How the Study Was Run
The design is described as randomized and placebo-controlled.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.
The t-test, Chi-square test, and repeated measures ANOVA were carried out in SPSS software (version 22) to analyze the data.
What Was Measured
Topics PubMed links to this paper include Urinary Incontinence, Stress, Vitamin D, Iran, Urinary Incontinence, Dietary Supplements, Vitamin D Deficiency and Quality of Life.
Author keywords: Premenopausal, Stress urinary incontinence and Vitamin D3.
What This Means in Plain Language
The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 60 women.
Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2022 (BMC women's health), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.