[Vitamin D level in umbilical cord blood of late preterm infants and the effect of vitamin D3 supplementation on the behavioral development of infants and young children: a prospective randomized controlled study].

Plain-language guide to PMID 36398542 (2022): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 161 infants.

Key Facts

PMID: 36398542
Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
Year: 2022
Study type: Randomized Controlled Trial
Authors: Hou QY et al. (3 authors)
DOI: 10.7499/j.issn.1008-8830.2206096

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

To investigate the level of 25 hydroxyvitamin D [25(OH)D] in late preterm infants and the effect of vitamin D3 supplementation on the neurobehavioral development of infants and young children.

Who Took Part

According to the abstract, 161 infants were involved.

The age groups tagged for this paper are infants, young children and children.

In this prospective study, 161 late preterm infants who were admitted from June 2017 to June 2020 were enrolled.

The neurobehavioral development levels were determined by the Gesell Developmental Scale at the corrected ages of 10 months and 18 months.

How the Study Was Run

The researchers set it up as a randomized study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

According to the level of 25(OH)D in umbilical cord blood, they were divided into three groups: sufficiency group (n=52), insufficiency group (n=53), and deficiency group (n=56).

The levels of 25(OH)D were measured at 3 months after birth and at the corrected ages of 10 months and 18 months.

What Was Measured

The subject headings attached to it are Cholecalciferol, Fetal Blood, Infant, Premature, Dietary Supplements and Vitamin D.

Author keywords: 25-Hydroxyvitamin D, Behavioral development, Gesell Developmental Scale and Late preterm infant.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 161 infants.

Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2022 (Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics), a journal based in China.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Vitamin D, K2, Magnesium and Zinc in the library

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.