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Changes in fatty acid levels after consumption of a novel docosahexaenoic supplement from algae: a crossover randomized controlled trial in omnivorous, lacto-ovo vegetarians and vegans.
Plain-language guide to PMID 36418565 (2023): double-blind randomized controlled trial of Copper (Supplement).
Key Facts
- PMID
- 36418565
- Journal
- European journal of nutrition
- Year
- 2023
- Study type
- Randomized Controlled Trial
- Authors
- García-Maldonado E et al. (4 authors)
- DOI
- 10.1007/s00394-022-03050-3
- Registered trial
- NCT04278482
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Copper (Supplement), published as a randomized controlled trial.
To determine serum fatty acids of lacto-ovo vegetarian (LOV), vegan (VEG) and omnivorous (OMN) adults, and to analyse the effects of consuming a docosahexaenoic acid (DHA) supplement of vegetable origin on fatty acid profile.
Who Took Part
By PubMed's age tags, the people studied were adults, both men and women.
A randomized, double-blind, placebo-controlled crossover design was conducted in healthy adults.
How the Study Was Run
In design terms this was a randomized, double-blind, placebo-controlled and crossover study.
The participants were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.
Neither the participants nor the staff measuring them knew who was on Copper (Supplement), so expectations could not easily colour the readings.
Some participants received a placebo instead of Copper (Supplement), giving a reference point.
Each person switched between Copper (Supplement) and the comparison at some point, usually with a gap in between.
Compliance and dietary intake were estimated and serum fatty acids were determined by gas chromatography.
Results were analysed by mixed linear models.
What Was Measured
Topics PubMed links to this paper include Vegans, Diet, Vegetarian, Vegetarians, Dietary Supplements, Docosahexaenoic Acids, Fatty Acids and alpha-Linolenic Acid.
Author keywords: Omega-3, Omega-6 and Supplementation.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement).
Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2023 (European journal of nutrition), a journal based in Germany.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.